Updated Guidance for Communicating PFAS Identification Confidence with Ion Mobility Spectrometry.

ABSTRACT: Over the past decade, global contamination from per- and polyfluoroalkyl substances (PFAS) has become apparent due to their detection in countless matrices worldwide, from consumer products to human blood to drinking water. As researchers implement nontargeted analyses (NTA) to more fully understand the PFAS present in the environment and human bodies, clear guidance is needed for consistent and objective reporting of the identified molecules. Confidence levels for small molecules analyzed and identified with high-resolution mass spectrometry (HRMS) have existed since 2014; however, unification of currently used levels and improved guidance for their application is needed due to inconsistencies in reporting and continuing innovations in analytical methods. Here, we (i) investigate current

SUBMITTER: Boatman AK 

PROVIDER: S-EPMC12424050 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature