Pregnancy urinary phenol biomarker concentrations in relation to serum levels of inflammatory cytokines: Results from the EARTH study.

ABSTRACT:

Background

Evidence on the association between maternal phenol exposure and inflammation during pregnancy is limited and inconsistent.

Objective

To evaluate associations between urinary phenol biomarkers and serum inflammatory cytokines across pregnancy, and to examine whether associations vary by trimesters.

Methods

We included 175 pregnant women from the Massachusetts General Hospital Fertility Center and participating in the Environment and Reproductive Health (EARTH) Study (2005-2017), with available data on urinary concentrations of eight phenol biomarkers and serum inflammatory biomarkers, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6). Linear regression models were employed to assess the association between individual phenol biomarker conc

SUBMITTER: Liang X 

PROVIDER: S-EPMC12424069 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature