RNA-seq reveals potential gene biomarkers in fathead minnows (<i>Pimephales promelas</i>) for exposure to treated wastewater effluent.

ABSTRACT: Discharged wastewater treatment plant (WWTP) effluent greatly contributes to the generation of complex mixtures of contaminants of emerging concern (CECs) in aquatic environments which often contain neuropharmaceuticals and other emerging contaminants that may impact neurological function. However, there is a paucity of knowledge on the neurological impacts of these exposures to aquatic organisms. In this study, caged fathead minnows (Pimephales promelas) were exposed in situ in a temperate-region effluent-dominated stream (i.e., Muddy Creek) in Coralville, Iowa, USA upstream and downstream of a WWTP effluent outfall. The pharmaceutical composition of Muddy Creek was recently characterized by our team and revealed many compounds there were at a low microgram to high na

SUBMITTER: Schumann PG 

PROVIDER: S-EPMC12424080 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature