Periodontitis and Oral Bacteria Related to Rheumatoid Arthritis: A Case-Control Study.

ABSTRACT:

Introduction and aims

This study compared periodontal status and oral bacteria between rheumatoid arthritis (RA) patients and healthy controls (HCs), and examined the influence of oral bacteria on the association between periodontitis and RA.

Methods

In total, 85 patients with RA and 119 HCs were enrolled. The oral microflora DNA test was used to quantify the oral bacterial species detected in gingival crevicular fluid. Probing depth and the clinical attachment level of the periodontal ligament were taken as parameters of periodontal status. Height, body weight, medical history, family history of RA, lifestyle habits, and stress were evaluated using a self-administered questionnaire. Univariate and multivariate logistic regression analyses were conducted to assess the associ

SUBMITTER: Hashimoto H 

PROVIDER: S-EPMC12424421 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature