The platelet and coagulation function parameters in late pregnancy are associated with preeclampsia and its severity: a single-center retrospective study.

ABSTRACT:

Objective

This study aimed to explore the correlation between platelet and coagulation function during late pregnancy with preeclampsia (PE) as well as its severity, and concurrently establish an effective risk model to predict PE.

Methods

As a retrospective case-control study, this research encompassed a sample of 594 patients of late pregnancy in Hangzhou Women's Hospital from January 2021 to April 2024, including 198 cases diagnosed with mild-PE, 198 with severe-PE, and 198 healthy pregnant women. Utilizing both univariate and multivariate analysis, this study conducted a comparison of demographic and laboratory data among these groups to uncover the correlation between platelet parameters, coagulation function, and PE as well as the severity. Ultimately, a receiver opera

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12424609 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature