Discovery of additional ancient genome duplications in yeasts.

ABSTRACT: Whole genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages^1,2, preceding adaptive radiations in vertebrates^3-5, teleost fish^6,7, and angiosperms^8,9. In contrast to the many known ancient WGDs in animals^10,11 and especially plants^12-14, we are aware of evidence for only four in fungi^15,16. The oldest of these occurred ~100 million years ago (mya) and is shared by ~60 extant Saccharomycetales species^17,18, including the baker's yeast Saccharomyces cerevisiae (Fig. 1). Notably, this is the only known ancient WGD in the yeast subphylum Saccharomycotina. The dearth of ancient WGD events in fungi remains a mystery¹⁵. Some studies have suggested that fungal

SUBMITTER: David KT 

PROVIDER: S-EPMC12424943 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature