Functional connectivity characteristics of epilepsy with anxiety: A resting-state functional near-infrared spectroscopy study.

ABSTRACT: Functional near-infrared spectroscopy (fNIRS) was applied to investigate the resting-state functional connectivity (RSFC) characteristics of the cerebral cortex in epileptic patients with and without anxiety. A total of 38 epileptic patients were recruited and divided into 2 groups according to the Generalized Anxiety Disorder 7-item score: epilepsy with anxiety (anxiety group) and epilepsy without anxiety (non-anxiety group). Resting-state fNIRS for 15 minutes was performed on each patient. Preprocessing of fNIRS data and RSFC analysis were performed in NirSpark software (Danyang Huichuang Medical Equipment Co., Ltd., China). Brain network was divided into 6 regions of interest (ROI). Based on the concentration of oxygenated hemoglobin in the time series, the RSFC strength was calculated.

SUBMITTER: Chen X 

PROVIDER: S-EPMC12425098 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature