Wildfire Smoke Induces Eye Surface Inflammation and Tear Film Changes in a Human Experimental Model.

ABSTRACT:

Purpose

To investigate the short-term impact of exposure to smoke from vegetation burns on ocular surface symptoms and signs.

Methods

Woody bushfuels were burnt in an enclosed room (Flammability Laboratory, University of Tasmania, Australia) to generate particulate matter and monitored in real time (Dust Trak II). Eighteen participants (aged 20-63 years, 8 males and 10 females) fitted with respirators were seated 1.5 m from the burn for 15 minutes. Clinical ocular surface measurements were conducted in the right eye. Tears were collected from the left eye and analyzed for the cytokine interleukin-1β (enzyme-linked immunosorbent assay). Pre- and postexposure differences were analyzed using paired t tests or Wilcoxon signed rank tests. Associations between symptoms and signs w

SUBMITTER: Jaiswal S 

PROVIDER: S-EPMC12425145 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature