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The prevalence of trachoma, ocular Chlamydia trachomatis infection and anti-Pgp3 antibodies in Choiseul Province, Solomon Islands.


ABSTRACT: Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, remains a leading infectious cause of blindness globally, with significant implications for public health. The World Health Organization and partners aim to eliminate trachoma as a public health problem by 2030, targeting specific prevalence thresholds for trachomatous trichiasis (TT) and trachomatous inflammation-follicular (TF). Diagnosis is primarily clinical. Studies have shown discrepancies between prevalence estimates of TF and C. trachomatis infection. This study, undertaken in Choiseul, Solomon Islands, evaluated TF, evidence of current C. trachomatis infection (by polymerase chain reaction (PCR) on conjunctival swabs), and evidence of past exposure to that bacterium (using anti-Pgp3 serology on dried blood s

SUBMITTER: Dyer CEF 

PROVIDER: S-EPMC12425259 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature