A retrospective cohort study evaluating the predictive value of urinary L-FABP combined with the SOFA score for assessing COVID-19 severity.

ABSTRACT: Although the symptoms of Coronavirus Disease 2019 (COVID-19) omicron strains are generally mild, some individuals with initially mild symptoms later required supplemental oxygen or hospitalization, while others died, highlighting the importance of rapid diagnosis and early treatment for such patients. Therefore, this study evaluated the benefit of a combined approach to identify individuals at risk of severe illness due to COVID-19 using urinary L-type fatty acid-binding protein (L-FABP) levels and the Sequential Organ Failure Assessment (SOFA) scores calculated from blood tests for pre-admission screening of patients with COVID-19. L-FABP, a non-invasive urine biomarker, and the SOFA score, an established method for assessing organ failure severity, were evaluated in conjunction with pati

SUBMITTER: Terakawa K 

PROVIDER: S-EPMC12425294 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature