An innovative submucosal filler for esophageal endoscopic submucosal dissection: A porcine model study (with video).

ABSTRACT:

Background

Esophageal endoscopic submucosal dissection (ESD) a more challenging procedure. Numerous studies have explored submucosal injection materials from diverse perspectives. However, there is no consensus yet, and further exploration is still required. This study aimed to evaluate the efficacy of a novel submucosal filler, acetylcysteine, which is commonly used in respiratory medicine, when applied for the first time in ESD procedure of the porcine esophagus.

Methods

A self-controlled survival study was carried out on porcine model. In each pig, the novel submucosal filler was injected in one part of the esophagus (Experimental group; Group E), while normal saline was injected in another part (Control group; Group C) during the ESD procedure. Additionally, one pig rece

SUBMITTER: Lin L 

PROVIDER: S-EPMC12425303 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature