The association between obstructive sleep apnoea and diabetic peripheral neuropathy in subjects with type 2 diabetes.

ABSTRACT:

Objective

This study aimed to examine the association between obstructive sleep apnoea (OSA) and diabetic peripheral neuropathy (DPN) in subjects with type 2 diabetes mellitus (T2DM).

Methods

A cross-sectional study was conducted involving 228 T2DM subjects at The First Hospital of Qinhuangdao. OSA was assessed using polysomnography. DPN was diagnosed based on clinical signs, symptoms and electromyography findings. Small fibre neuropathy was additionally assessed through corneal confocal microscopy. Among these T2DM subjects, 124 (54.4%) had DPN. The prevalence of OSA was 67.5% (mild OSA 30.7%, moderate-to-severe OSA 36.8%). DPN prevalence rates were 40.5%, 52.9% and 67.9% in subjects without OSA, with mild OSA, and with moderate-to-severe OSA respectively. Multiple logistic

SUBMITTER: Lu N 

PROVIDER: S-EPMC12425751 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature