Association of pan-immune-inflammation value and atherogenic index of plasma with chronic coronary syndrome in non-alcoholic fatty liver disease patients.

ABSTRACT:

Background

Non-alcoholic fatty liver disease (NAFLD) is linked to a higher risk of cardiovascular disease, particularly chronic coronary syndrome (CCS). However, reliable biomarkers for early CCS risk stratification in NAFLD patients remain lacking. This study aims to assess the pan-immune-inflammation value (PIV) and atherogenic index of plasma (AIP) for CCS in NAFLD patients and to construct a practical tool for personalized risk assessment.

Methods

This retrospective study included 459 NAFLD patients undergoing coronary angiography. Least absolute shrinkage and selection operator (LASSO) and multivariate logistic regression were used to discover independent risk variables for CCS. A nomogram was constructed to quantify CCS risk. Model performance was evaluated by calibrat

SUBMITTER: Yu B 

PROVIDER: S-EPMC12425755 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature