Reorganization of brain networks in olfactory groove meningioma patients: a pilot resting-state fMRI study.

ABSTRACT:

Background

Olfactory groove meningioma (OGM) is frequently associated with neuropsychological and behavioral impairments. However, there is currently a lack of evidence on the pathobiology of these functional alterations. In this study, our objective was to evaluate functional connectivity disturbances in patients with OGMs compared to healthy controls.

Methods

Nineteen patients with OGMs and twenty healthy controls were enrolled. The seed-based functional connectivity analysis used the main hubs of the default mode network (DMN), salience network (SN), and fronto-parietal network (FPN) as seeds. Region-of-interest (ROI)-to-voxel second-level analysis was conducted, revealing the most significant clusters of differences in brain functional connectivity between the groups.

SUBMITTER: Filimonova E 

PROVIDER: S-EPMC12425792 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature