Association between <i>Helicobacter pylori</i> infection and serum uric acid levels in a Chinese community population: a cross-sectional study stratified by renal function.

ABSTRACT:

Background

The relationship between Helicobacter pylori (H. pylori) infection and serum uric acid levels remains debated. This study investigates the association between H. pylori infection and serum uric acid levels in a Chinese community, exploring renal function as a potential modifier.

Methods

We conducted a cross-sectional study involving 8,439 adults who underwent health examinations at a hospital in Wuhan from January 2022 to January 2024. H. pylori infection was assessed via the 14C-urea breath test, and serum uric acid levels were measured by the uricase method. Multivariable linear regression models evaluated the associations, and interaction analysis identified potential effect modifiers. Subgroup analyses were stratified by estimated g

SUBMITTER: Wang K 

PROVIDER: S-EPMC12425895 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature