Increased cardiovascular disease risk among adolescent and young adult survivors of cervical cancer.

ABSTRACT:

Objective

To investigate the incidence and risk factors of cardiovascular disease (CVD) in adolescent and young adult survivors of cervical cancer.

Methods

This retrospective cohort study used data from the Korean National Health Insurance Service. Adolescent and young adult (AYA) cervical cancer survivors (n=7,803) were matched with non-cancer controls (n=23,327) using 1:3 propensity score matching, and hazard ratios (HRs) for CVD were determined using Cox regression models. Multivariable Cox regressions were used to assess CVD incidence according to cancer treatment and identify risk factors.

Results

A total of 7,803 AYA survivors with cervical cancer were analyzed in this study during a median 8.9 years of follow-up. They developed any CVD with an adjusted HR of 1.

SUBMITTER: Choi HL 

PROVIDER: S-EPMC12426736 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature