Quantifying the impact of bladder complications following gynecological cancer treatment: systematic review and meta-regression.

ABSTRACT:

Objective

Gynecological cancer treatments, including radiotherapy (RT) and chemotherapy, leads to various bladder complications. The anatomical proximity of the treatment site to the urinary bladder primarily explains the complications following RT, while chemotherapy contribute to bladder dysfunction through systemic mechanisms. This study systematically reviews the nature, extent, and prevalence of bladder complications among women treated for these malignancies, underscoring the influence of treatment modalities on bladder function.

Methods

A comprehensive search of databases including Embase, Scopus, PubMed/MEDLINE, CINAHL, and the Cochrane Library was conducted, focusing on women undergoing RT, chemotherapy, or both for gynecological cancers. Meta-regression was perform

SUBMITTER: Rotem R 

PROVIDER: S-EPMC12426742 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature