Sex differences in risk factors for unsuccessful tuberculosis treatment outcomes in Eastern Europe from 2020 to 2022: a multi-country retrospective cohort study.

ABSTRACT:

Background

Addressing the disproportionate representation between sexes is essential for achieving universal health coverage. Studies on the association between sex and unsuccessful tuberculosis treatment outcomes have shown conflicting results. This study examines this association and analyses sex-stratified risk factors associated with unsuccessful outcomes.

Methods

This retrospective, observational cohort study analysed prospectively collected data from six Eastern European countries from 2020 to 2022. Treatment outcomes were defined using World Health Organization criteria. Uni- and multivariable logistic regression models were used to assess the association between sex and unsuccessful outcomes ('treatment failure', 'lost to follow-up', 'died', or any of these). After p

SUBMITTER: Skouvig Pedersen O 

PROVIDER: S-EPMC12426823 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature