Triple Assessments of Atherosclerosis in Patients With Heterozygous Familial Hypercholesterolemia.

ABSTRACT:

Background

Data on the appropriate timing and impact of atherosclerosis assessment in patients with heterozygous familial hypercholesterolemia (HeFH) are limited.

Objectives

The authors aimed to determine when atherosclerotic changes occur and the utility of triple assessments of carotid plaque, coronary plaque, and coronary artery calcium (CAC) in patients with HeFH.

Methods

Data from patients with HeFH in the primary prevention setting admitted to Kanazawa University Hospital between 2000 and 2020 who underwent triple atherosclerosis assessment and were followed up were retrospectively reviewed (n = 622, male = 306, mean age = 54 ± 13 years). Risk factors for coronary heart disease events were determined using the Cox proportional hazard model. Carotid plaque, coron

SUBMITTER: Tada H 

PROVIDER: S-EPMC12426841 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature