Systolic Dyssynchrony Index in Hypertrophic Cardiomyopathy: Association With Ventricular Arrhythmias and Risk Prediction.

ABSTRACT:

Background

Mechanical dispersion (MD) has been demonstrated to be associated with nonsustained ventricular tachycardia (NSVT) and could potentially predict sudden cardiac death in hypertrophic cardiomyopathy (HCM) patients.

Objectives

The authors sought to evaluate the systolic dyssynchrony index (SDI) measured with 3-dimensional echocardiography and explore its predictive value for risk assessment in HCM patients.

Methods

A total of 610 HCM patients were prospectively enrolled, and we measured the MD and SDI. Their associations with NSVT and guideline-based implantable cardioverter-defibrillator class of recommendation (ICD-COR) were analyzed.

Results

A total of 81 (13.28%) patients were diagnosed with NSVT by the 24-hour Holter monitoring. The SDI of HCM pati

SUBMITTER: Wang R 

PROVIDER: S-EPMC12426848 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature