Serious adverse events associated with bowel preparation for colonoscopy in Japan: Systematic review.

ABSTRACT:

Objectives

Bowel preparation for colonoscopy can lead to serious adverse events (AEs), raising significant safety concerns in colorectal cancer (CRC) screening. A systematic review of these serious AEs in Japan was performed to explore potential management strategies.

Methods

The Ovid-MEDLINE and Ichushi databases were searched from inception to March 2024. Domestic studies that reported serious AEs in adults aged 18 years and older who were administered bowel cleansing agents or laxatives for a scheduled colonoscopy, regardless of its purpose, were extracted. Serious AEs were defined as those requiring hospitalization or extended hospital stays. Selected studies were assessed for quality verification using the established checklist.

Results

A total of 5049 articles w

SUBMITTER: Tadano T 

PROVIDER: S-EPMC12427159 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature