Prognostic Value of the Level of Urine Dipstick Proteinuria in Gastric Cancer in the Korean Population.

ABSTRACT:

Background/objectives

Proteinuria, a marker of renal dysfunction, has been implicated in cancer risk, yet its role in gastric carcinogenesis remains underexplored in high-incidence populations. This study evaluated the association between urine dipstick proteinuria severity and gastric cancer incidence in a nationwide Korean cohort.

Methods

We analyzed data from the Korean National Health Insurance Service-National Sample Cohort, including 220,941 adults aged > 40 years, without a diagnosis of cancer, who received health examinations in 2009. Proteinuria was classified by single dipstick testing as negative, 1+, or ≥2+. Participants were followed for a mean of 4.37 ± 0.49 years (965,601.2 person-years). Multivariable Cox proportional hazards models adjusted for age, sex, bod

SUBMITTER: Sohn YJ 

PROVIDER: S-EPMC12427291 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature