Functional role of <i>FvMdm10</i> in stress response, pathogenicity, and fumonisins production in <i>fusarium verticillioides</i>.

ABSTRACT: Endoplasmic reticulum-mitochondrial encounter structure (ERMES), the protein complex that tethers mitochondria and endoplasmic reticulum, is critical for mitochondrial functions and various cellular processes. Our preliminary studies showed that mitochondrial integrity was critical for fumonisin biosynthesis. However, the biological roles of ERMES and its subunits in phytopathogenic fungi, especially their roles in the regulation of fumonisin biosynthesis remain ambiguous. In this current study, we investigated the biological functions of FvMdm10, the core component of ERMES, in the fumonisin-producing fungus Fusarium verticillioides. The gene-deletion mutant ΔFvMdm10 exhibited attenuated virulence on intact maize kernels compared with the wild-type strain M3125, which partially att

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC12427440 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature