Clinical Deterioration in Dogs with Idiopathic Epilepsy Caused by <i>E. coli</i> Urinary Tract Infection.

ABSTRACT: Idiopathic epilepsy (IE) is a common chronic neurological disorder in dogs, and both its comorbidities and adverse effects of anti-seizure medication (ASM) can markedly reduce quality of life (QoL) for affected dogs and their caregivers. Concurrent conditions such as lower urinary tract infections (UTIs) may mimic ASM side effects or signs of disease progression, potentially leading to inappropriate dose adjustment or treatment discontinuation. This retrospective case series describes eight dogs with IE and Escherichia coli (E. coli) UTI, presenting with suspected worsening of ASM side effects. Reported deterioration lasted 1-55 days (mean 31), with behavioral changes (n = 5), lethargy (n = 5), new or worsened ataxia (n = 5), urinary incontinence (n = 3), polyuria (n = 3), po

SUBMITTER: Reeh S 

PROVIDER: S-EPMC12427457 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature