Colon Capsule Endoscopy as a Promising Diagnostic Tool in Colorectal Cancer: A Systematic Review and Network Meta-Analysis.

ABSTRACT: Background: Early detection and prevention of colorectal cancer (CRC) are key goals of population-based screening. Several diagnostic tests have been proposed for CRC screening. This study compares the diagnostic accuracy of colon capsule endoscopy (CCE), colonoscopy (COL) and computed tomographic colonography (CTC), focusing on risk factors such as polyps. Methods: We conducted a systematic review with meta-analyses and network meta-analysis. Pooled estimates of sensitivity (SE), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV) were calculated using a random-effects model. Diagnostic performance was assessed for first- and second-level screening based on effect size estimates. Results: For first-level screening, sensitivity was 0.7

SUBMITTER: Altobelli E 

PROVIDER: S-EPMC12427630 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature