Light and Shadows: Insights from Large-Scale Visual Screens for Arabidopsis Leaf Morphology Mutants.

ABSTRACT: Screens for specific phenotypes have long been a cornerstone of biology. Here, we present an updated synthesis of our large-scale visual screens for Arabidopsis (Arabidopsis thaliana) mutants that exhibit leaf morphology defects. In our 2009 review, we used phenotypes to group the leaf mutants that we had isolated and characterized since 1992; here, by contrast, we functionally classified the mutations that we studied over the last 16 years based on the biological programs they disrupt. Since 2009, we have identified and analyzed 38 genes required for proper leaf development; these genes are involved in translation, chloroplast function, cell wall construction, auxin homeostasis, microRNA biogenesis, and epigenetic regulation. Many of the identified mutants have pleiotropic phenotyp

SUBMITTER: Juan-Vicente L 

PROVIDER: S-EPMC12427647 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature