Functioning and Safety of the Non-Invasive Corneal Esthesiometer Brill: A Multicenter Study.

ABSTRACT: Background/Objectives: Corneal sensitivity can be decreased by several ocular conditions, including dry eye and refractive surgery, which can lead to ocular epithelial lesions. This decrease can be detected by esthesiometry. The main objective of this study was to evaluate the performance, safety, and efficacy of the Corneal Esthesiometer Brill in healthy subjects without ocular pathologies. Methods: A controlled, randomized, prospective, multicenter pilot clinical study was conducted in adult patients with healthy eyes. Corneal sensitivity measurements were made three times for one eye randomly selected to obtain the corneal sensitivity reference ranges. Additionally, one more measurement was taken after the application of a topical anesthetic. An intra- and inter-observer a

SUBMITTER: Renedo Laguna C 

PROVIDER: S-EPMC12427739 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature