Improved Prognostic Stratification with the FIGO 2023 Staging System in Endometrial Cancer: Real-World Validation in 2969 Patients.

ABSTRACT:

Background/objectives

To assess the impact of the 2023 FIGO staging revision on stage distribution, survival outcomes, and prognostic performance in endometrial cancer compared to the 2009 system.

Methods

This retrospective cohort study analyzed 2969 patients with FIGO 2009 stage I-III endometrial cancer diagnosed at Samsung Medical Center (1994-2023). Patients were reclassified per the 2023 FIGO system. Stage migration, progression-free survival (PFS), and overall survival (OS) were evaluated. Prognostic performance was compared using the Akaike information criterion (AIC), Bayesian information criterion (BIC), concordance index (C-index), and area under the receiver operating characteristic curve (AUC).

Results

Stage migration occurred in 20.2% of patients, with 98.

SUBMITTER: Seo JH 

PROVIDER: S-EPMC12427876 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature