Norepinephrine Onset Time and Mortality in Patients with Septic Shock Treated in the Emergency Department.

ABSTRACT: Introduction: Sepsis, and particularly septic shock, is a life-threatening condition associated with high mortality rates in the emergency department. Timely interventions can significantly reduce these unacceptably high mortality rates. While some studies have demonstrated reduced mortality with early norepinephrine initiation, there is limited research on this intervention specifically within the emergency department setting. The objective of this study was to determine the association between the time to norepinephrine initiation in the emergency department and in-hospital mortality in adult patients diagnosed with septic shock. Methods: This retrospective cohort study included adult patients diagnosed with septic shock in the emergency department. Demographics, paraclinic

SUBMITTER: Devia Jaramillo G 

PROVIDER: S-EPMC12429137 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature