Contrast-enhanced CT as a non-invasive alternative for lung shunt fraction estimation in hepatic transarterial radioembolization.

ABSTRACT:

Background

Estimation of the lung shunt fraction (LSF) is an integral part of liver radioembolization treatment planning to prevent excessive lung irradiation from arterio-venous shunting in the liver. ^99mTc macro-aggregated albumin (^99mTc-MAA) nuclear imaging is the standard method. Recent literature suggests that ^99mTc-MAA nuclear imaging may be omitted in selected patient populations.

Purpose

This study investigates the potential of contrast-enhanced computed tomography (CECT) as a non-invasive method for estimating LSF as an alternative for ^99mTc-MAA nuclear imaging.

Materials and methods

This single-center retrospective study included 30 consecutive patients who underwent ⁹⁰Y radioembolization between January

SUBMITTER: Mehadji B 

PROVIDER: S-EPMC12429231 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature