The Use of Advanced Glycation End-Product Measurements to Predict Post-Operative Complications After Cardiac Surgery.

ABSTRACT: Background/Objectives: Frailty is increasingly recognised as an important contributor to outcomes following cardiac surgery. There are various measures of frailty described, but many include subjective assessments impacting reliability and reproducibility of measurement. A potential biomarker: advanced glycation end products (AGEs) have been suggested to closely correlate with frailty. This may offer the opportunity to objectively measure frailty and have potential use in preoperative risk assessment. The objective and aim of this narrative review is to assess the association between AGEs and outcomes following surgery, in order to evaluate the use of AGEs for preoperative risk assessment. Methods: This review involved searching five databases including the following: MEDLINE

SUBMITTER: Agrawal DS 

PROVIDER: S-EPMC12429286 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature