Proteomic Insights into Childhood Obesity: A Systematic Review of Protein Biomarkers and Advances.

ABSTRACT: Childhood obesity has emerged as one of the most pressing public health challenges of the 21st century. Early-onset obesity is associated with an increased risk of developing numerous comorbidities later in life. Despite extensive research into its multifactorial etiology-including genetic, behavioral, environmental, and socioeconomic factors-the precise molecular mechanisms underlying the development and persistence of obesity in the pediatric population remain incompletely understood. Proteomics offers promising insights into these mechanisms. The application of proteomics in pediatric obesity research has grown, enabling the identification of proteins that reflect dynamic changes in metabolic and inflammatory pathways. This advancement allows clinicians to move beyond traditional anthro

SUBMITTER: Krakowczyk D 

PROVIDER: S-EPMC12429325 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature