Correlation Between Urinary Osteopontin Concentration and the Mineral Content and Composition of Kidney Stones.

ABSTRACT: Background and Objective: Information about the type of kidney stones is important for informed therapeutic decisions and the prevention of urolithiasis. Urinary stones are heterogeneous, and their elemental composition and crystal structure vary between patients. The formation of urinary stone deposits depends, among other things, on physiological conditions, the concentration of promoters and inhibitors of crystallization, and proteins found in the urine. The aim of this study was to determine differences in urine osteopontin (OPN) levels between groups of different stone-formers. Methods: Urinary stone specimens (n = 44) were acquired during elective endoscopic procedures. Specimens were divided into subgroups by k-means cluster analysis depending on calcium and pho

SUBMITTER: Jaromin M 

PROVIDER: S-EPMC12429501 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature