Sex Differences in Seasonal Variation in Metabolic Syndrome and Its Components: A 10-Year National Health Screening Study.

ABSTRACT: Background/Objectives: Metabolic syndrome (MetS) comprises a cluster of cardiometabolic risk factors that vary dynamically under environmental and behavioral influences. Although there are data suggesting seasonal variability in individual metabolic components, few studies have comprehensively assessed MetS as a composite condition across seasons using a large, nationally representative population. In this study, we aimed to evaluate the seasonal and monthly patterns of MetS prevalence and component burden, with a focus on sex-specific differences. Methods: We analyzed 5,507,251 health screening records from 2,057,897 Korean adults aged ≥40 years between 2013 and 2022, obtained from the National Health Insurance Service database. Seasons were categorized as: spring (March-May

SUBMITTER: Kim HS 

PROVIDER: S-EPMC12429781 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature