In-Depth Exploration of Chemical Constituents from <i>Justicia procumbens</i> L. Through UHPLC-Q-Exactive Orbitrap Mass Spectrometry.

ABSTRACT: Justicia procumbens L. (JP) has been traditionally used to treat colds with fever, swollen and sore throat, jaundice, malaria and eczema. Studies indicate that lignans constitute the primary bioactive components, yet systematic phytochemical investigations remain limited. Therefore, it is necessary to establish a rapid and effective method to identify the chemical components in JP. In this study, ultra-high-performance liquid chromatography-quadrupole-Exactive Orbitrap mass spectrometry (UHPLC-Q-Exactive Orbitrap MS) coupled with parallel reaction monitoring (PRM) was used for the first time to investigate JP. Based on chromatographic retention times, MS and MS² data, and bibliography data, a total of 132 compounds were tentatively identified, including 54 lignans, 19 flavonoids, 31

SUBMITTER: Guan L 

PROVIDER: S-EPMC12430035 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature