Comparative Study of Ni(II) Complexes with Dithiocarbazate- and Thiosemicarbazone-Based Ligands: Synthesis, Crystal Structures, and Anticancer Activity.

ABSTRACT: The present work reports a comparative study of thiosemicarbazone (H₂L¹) and dithiocarbazate (H₂L²) ligands and their Ni(II) complexes; [Ni(L¹)(PPh₃)] (1); [Ni(L¹)(Py)] (2); [Ni(L²)(PPh₃)] (3); and [Ni(L²)(Py)] (4). All compounds were characterized by spectroscopy analysis; and the complexes were also characterized by single-crystal X-ray diffraction. The crystal structures of the complexes revealed a distorted square planar geometry with the Ni(II) atoms coordinated to a double-deprotonated and tridentate ligand molecule by the ONS donor system. The coordination sphere is completed by the incorporation of pyridine or triphenylphosphine coligands

SUBMITTER: Pessoa GS 

PROVIDER: S-EPMC12430362 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature