Bioengineered Chitosan-Collagen-Honey Sponges: Physicochemical, Antibacterial, and In Vitro Healing Properties for Enhanced Wound Healing and Infection Control.

ABSTRACT: Bacterial-mediated infections represent a major risk factor for chronic wounds. Numerous polymeric dressings have been proposed to reduce this incidence and promote wound healing. In the present investigation, chitosan/collagen/honey-based sponges were prepared by freeze-drying. The effect of honey incorporation at different concentrations on the physicochemical and antibacterial properties of the sponges was evaluated. The SEM images showed that the surface and cross-sections of all samples had a porous structure. The pore size gradually increased in the range of 78.14 to 126.9 μm due to the increase in honey content in the sponges. This property resulted in considerably higher porosity degrees (79.90-90.13%) and absorption rates (ranges of 1357-1665% in deionized water and 865-1938% in P

SUBMITTER: Servin de la Mora-Lopez D 

PROVIDER: S-EPMC12431070 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature