Passive Measures of Physical Activity and Cadence as Early Indicators of Cognitive Impairment: Observational Study.

ABSTRACT:

Background

Emerging research suggests that regular physical activity can reduce the risk of cognitive decline. However, most prior studies rely on self-reported measures, which are subject to recall bias, subjectivity, and limited temporal resolution.

Objective

This study aims to investigate whether objectively measured physical activity, captured through passive accelerometry, is associated with incident cognitive impairment and neuropsychological test performance and to evaluate its potential as an early indicator of cognitive decline.

Methods

We analyzed data from the Framingham Heart Study (FHS), a community-based cohort with longitudinal surveillance of cognitive impairment. Participants wore an Actical accelerometer for at least 3 days (excluding bathing). A tot

SUBMITTER: Ding H 

PROVIDER: S-EPMC12431165 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature