Self-Sensing with Hollow Cylindrical Transducers for Histotripsy-Enhanced Aspiration Mechanical Thrombectomy Applications.

ABSTRACT: Intravascular aspiration thrombectomy catheters are widely used to treat stroke, pulmonary embolism, and deep venous thrombosis. However, their performance is frequently compromised by clot material becoming lodged within the catheter tip. To address this, we develop a novel ultrasound-enhanced aspiration catheter approach that generates cavitation within the tip to mechanically degrade clots, with a view to facilitate extraction. The design employs hollow cylindrical transducers that produce inwardly propagating cylindrical waves to generate sufficiently high pressures to perform histotripsy. This study investigates the feasibility of self-sensing cavitation detection by analyzing voltage signals across the transducer during treatment. Experiments were conducted for two transmit pulse len

SUBMITTER: Gong L 

PROVIDER: S-EPMC12431187 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature