Analytical approach of synchronous and asynchronous update schemes applied to solving biological Boolean networks.

ABSTRACT: Characterizing the minimum, necessary and sufficient components to generate the dynamics of a biological system has always been a priority to understand its functioning. In this sense, the canonical form of biological systems modeled by Boolean networks accurately defines the components in charge of controlling the dynamics of such systems. However, the calculation of the canonical form might be complicated in mathematical terms. In addition, computing the canonical form does not consider the dynamical properties found when using the synchronous and asynchronous update schemes to solve Boolean networks. Here, we analyze both update schemes and their connection with the canonical form of Boolean networks. We found that the synchronous scheme can be expressed by the Chapman-Kolmogorov equati

SUBMITTER: Bensussen A 

PROVIDER: S-EPMC12431216 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature