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Albumin-corrected anion gap as a predictive marker for mortality in critically Ill cirrhosis patients: an analysis based on the MIMIC-IV database.


ABSTRACT:

Background

The prognostic value of Albumin-Corrected Anion Gap (ACAG) has been extensively examined across a range of diseases; however, its relationship with short- and long-term survival in critically ill cirrhotic patients remains poorly understood. This study aims to investigate and elucidate the association between ACAG levels and mortality risk in this patient population.

Methods

Initial analysis involved a univariate assessment of 30-day mortality outcomes, followed by stratification of patient data using X-tile software. Multivariate modeling was employed to identify independent risk factors for mortality. Survival outcomes associated with ACAG levels were analyzed using Kaplan-Meier (K-M) survival curves, while diagnostic accuracy was evaluated through Receiver Oper

SUBMITTER: Xu C 

PROVIDER: S-EPMC12431220 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature