Phytochemical profiling and bioactivity validation of Moringa oleifera leaves: Antimicrobial, antidiarrheal, analgesic, and in silico insights.

ABSTRACT: The increasing threat of antimicrobial resistance and the need for new medicines have renewed interest in medicinal plants like Moringa oleifera Lam., a fast-growing tree from the Moringaceae family that can survive in dry conditions. It is easily recognized by its compound leaves and long seed pods. Traditionally, it has been widely used in Ayurvedic medicine and as a nutrient-rich food source, with its leaves, pods, and seeds employed for treating malnutrition, inflammation, and over 300 ailments across South Asia and Africa. A methanolic leaf extract was prepared and analyzed via GC-MS/MS for phytoconstituents. Antimicrobial activity was tested against Gram-positive, Gram-negative bacteria, and fungi using disc diffusion (100 µg/disc), compared to standard antibiotics (30 µg/disc). Anti

SUBMITTER: Taher MA 

PROVIDER: S-EPMC12431276 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature