Diversity of Salmonella enterica isolates from urban river and sewage water in Blantyre, Malawi.

ABSTRACT:

Background

Salmonella enterica encompasses over 2,600 serovars, including several commonly associated with severe infection in humans. Salmonella is a major cause of sepsis in Africa; however, diagnosis requires clinical microbiology facilities. Environmental surveillance has the potential to play a role in Salmonella surveillance.

Methods

We undertook water-based environmental surveillance in Blantyre, Malawi, from 2018-2020, taking samples from rivers (87.9%), a sewage plant (8.85%) and other water sources (3.24%), isolating and storing 1,042 non-typhoidal Salmonella (NTS) isolates in this period. Of these, 341 NTS isolates were whole genome sequenced, genome quality was checked, duplicate genomes from any given sample were removed and core genome phylogeny was reconstruct

SUBMITTER: Rigby J 

PROVIDER: S-EPMC12431665 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature