Intentional Weight Loss and Associated Cancer Incidence Among People With Overweight or Obesity: A Systematic Literature Review.

ABSTRACT:

Aims

While obesity is linked to increased cancer risk, evidence on the impact of intentional weight loss on obesity-associated cancers (OACs) is limited. A systematic literature review (SLR) was conducted to assess the association between intentional weight loss and cancer incidence, including overall cancers and 13 OACs, from recent observational studies and clinical trials.

Methods

Studies published between January 2019 and May 2023 were searched within MEDLINE, EMBASE, and CENTRAL. Studies assessing the relationship between intentional weight loss, defined as weight reduction via metabolic-bariatric surgery (MBS) or lifestyle interventions, and cancer incidence were included. A dual independent review process was used to screen 1954 abstracts and 84 full-text articles, an

SUBMITTER: Liao CY 

PROVIDER: S-EPMC12432335 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature