Risk Factors for Patient-Important Upper Gastrointestinal Bleeding.

ABSTRACT: Rationale: Patient-important gastrointestinal bleeding is an endpoint developed by patients and family members; however, risk factors for this outcome are unknown. Objectives: We sought to identify risk factors for patient-important upper gastrointestinal bleeding among invasively ventilated adults. Methods: This preplanned regression analysis of an international trial database evaluated baseline and time-varying risk factors in the preceding 3 days for patient-important upper gastrointestinal bleeding, accounting for illness severity and the competing risk of death. Measurements and Main Results: Patient-important upper gastrointestinal bleeding occurred in the ICU among 131 of 4,821 (2.7%) patients. Baseline APACHE II score-hazard ratio (HR), 1.24 (95% confide

SUBMITTER: Deane AM 

PROVIDER: S-EPMC12432427 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature