Analysis of clinicopathological characteristics and prognosis of appendiceal neuroendocrine tumors: a retrospective cohort study based on the SEER database.

ABSTRACT:

Background

Appendiceal neuroendocrine tumors (ANETs) are rare, and there is a pressing clinical need for population-level data on their clinicopathological characteristics and prognosis to guide clinical decision-making. This study aimed to investigate the clinicopathological features and prognostic outcomes of patients with ANETs using the Surveillance, Epidemiology, and End Results (SEER) database.

Methods

We included patients diagnosed with ANETs from 2000 to 2020. Participant inclusion was based on confirmed ANET diagnosis in the SEER database. Clinical factors, including tumor grade, stage, surgical status, and patient demographics, were assessed. Patients were followed up through the SEER database to record survival outcomes. The Kaplan-Meier method and Cox proportiona

SUBMITTER: Ren X 

PROVIDER: S-EPMC12432788 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature