Global burden of gastric cancer attributed to high-salt diets: spatiotemporal trends and socio-demographic inequalities from 1990 to 2021.

ABSTRACT:

Background

Gastric cancer (GC) remains a major global health burden. High-salt diets are a key modifiable risk factor, promoting mucosal damage, chronic inflammation, and increased susceptibility to Helicobacter pylori infection. This study aimed to quantify the global, regional, and national GC burden attributable to high-salt diets and assess spatiotemporal trends and socio-demographic disparities from 1990 to 2021.

Methods

This study used data from the Global Burden of Disease (GBD) 2021 to assess the burden of GC attributable to high sodium intake. Mortality and disability-adjusted life years (DALYs) were estimated across 204 countries and territories from 1990 to 2021. Age-standardized mortality rate (ASMR) and age-standardized DALY rate (ASDR) were stratified by Socio-

SUBMITTER: Liu W 

PROVIDER: S-EPMC12432912 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature