Efficacy of stereotactic body radiotherapy in hepatocellular carcinoma with adrenal metastases: a retrospective analysis.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) with adrenal metastasis is associated with poor prognosis and lacks standardized treatment strategies. Stereotactic body radiotherapy (SBRT) is a promising non-invasive option, yet its efficacy in this setting remains underexplored. This study aims to evaluate the efficacy and safety of SBRT in managing HCC patients with adrenal metastasis, focusing on factors influencing local control (LC) and overall survival (OS).

Methods

This retrospective study included 52 HCC patients with adrenal metastases treated with SBRT using the CyberKnife system between February 2016 and March 2022. Gross tumor volume (GTV) and biologically effective dose (BED) were calculated, and LC and OS were analyzed. Prognostic factors were assessed using univaria

SUBMITTER: Cheng X 

PROVIDER: S-EPMC12432914 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature