Poorer prognosis of early gastric cardia cancer compared to early gastric non-cardia cancer: evidence from SEER database analysis.

ABSTRACT:

Background

Limited evidence and contradictory results exist regarding lymph node metastasis (LNM) and prognosis in early gastric cardia cancer (EGCC) and early gastric non-cardia cancer (EGNCC). This study aims to compare the clinicopathological features, LNM patterns, and survival outcomes between EGCC and EGNCC using a large population-based dataset.

Methods

This study utilized data from the Surveillance, Epidemiology, and End Results (SEER) population and employed multivariate analysis, Kaplan-Meier method, propensity score matching (PSM), and nomogram analysis to achieve comprehensive insights.

Results

EGCC tended to be younger in age, intestinal type, smaller tumor size, and well-differentiated type (P<0.05). No positive association was found between LNM and tumo

SUBMITTER: Ma S 

PROVIDER: S-EPMC12432917 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature