Establishment of a prognostic nomogram for intrahepatic cholangiocarcinoma patients receiving chemotherapy: a SEER-based study.

ABSTRACT:

Background

Chemotherapy is an important treatment for intrahepatic cholangiocarcinoma (ICC) patients, but there is a lack of survival prediction models. This study aims to develop a nomogram to predict cancer-specific survival (CSS) in ICC patients receiving chemotherapy.

Methods

A retrospective analysis was performed using data from the Surveillance, Epidemiology, and End Results (SEER) database involving 1,363 ICC patients who receiving chemotherapy between 2010 and 2019. The patients were randomly allocated in a 7:3 ratio to the training cohort and validation cohort. Cox proportional hazards regression analysis was employed to identify prognostic factors for nomogram construction. The accuracy of the model was assessed using the concordance index (C-index), area under the

SUBMITTER: Heng Q 

PROVIDER: S-EPMC12432954 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature